Denis L.J. Lafontaine received a research MSc (1991) and a PhD (1995) in Molecular Biology & Genetics from the University of Namur (Belgium) under the supervision of feu Prof Jean Vandenhaute. He conducted post-doctoral training (1995-2001) with Prof David Tollervey in the Gene Expression program at the European Molecular Biology Laboratory (EMBL, Heidelberg) and The Welcome Trust Center for Cell Biology at the University of Edinburgh. Denis was recruited to a permanent position with the Belgian F.R.S./FNRS in 2001, and since then has worked as a Principal Investigator at the Institute of Molecular Biology & Medicine at the University of Brussels. Denis is currently a Professor at the University of Brussels, a Professor at the University of Mons, and a Research Director with the F.R.S./FNRS. He is a co-founder and co-director of a preclinical imaging center, the Center for Microscopy and Molecular Imaging (Cmmi). He co-organized the International Ribosome Synthesis Meeting in 2012 (Banff, Canada), in 2015 (Brussels, Belgium), and in 2018 (Magog, Canada). In 2017, he was appointed as Dissemination Officer for the COST project Epitran on Epitranscriptomics. In 2018, he joined the ULB-Cancer Research Center (U-CRC). He is involved in an international Master on RNA Biochemistry at the University of Lorraine and is acting as a referee for journals in the field of Molecular and Cellular Biology, and for international funding agencies.