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Translacore is networking scientists involved in translational control in cancer

Translacore is a COST action (CA21154) aiming to develop a European network of excellence to foster basic research on mRNA translation in cancer. Translacore training school in Bioinformatics with Prof. Ola Larsson’s team, September 11-14, 2023, Karolinska Institutet, Stockholm, Sweden Biennale 2023: Where Science Meets Art, “Cycle of Health and…
Ribosome Fingerprints to help Cancer Diagnosis

In an amazing collaboration with the Eva Maria Novoa Lab (CRG, Barcelona, Spain), … Milenkovic et al. demonstrate that rRNA modifications are differentially modified across tissues, developmental stages, and in disease. The authors show that rRNA modification patterns, also termed “epitranscriptomic rRNA fingerprints” are sufficient to accurately identify tissue of…
RNA Society Meeting 2024. Thank you Edinburgh! May 28-June 2
EMBO RIBOSOME 2022, August 17-21, Engelberg
Fibrillarin is required for Neural Crest Cell maturation

Ribosomes are essential nanomachines responsible for protein production in all cells. Ribosomopathies are diseases caused by improper ribosome formation due to mutations in ribosomal proteins or ribosome assembly factors. Such diseases primarily affect the brain and blood, and it is unclear how malfunctioning of a process as general as ribosome…
The “iNo score”: Towards bringing the nucleolus in the clinics

Using the iNo score to discriminate normal from altered nucleolar morphology, with applications in basic cell biology and potential in human disease diagnostics Ribosome biogenesis is initiated in the nucleolus, a cell condensate essential to gene expression, whose morphology informs cancer pathologists on the health…